NucSys Meeting, June 14 - 17, 2007
University of Birmingham, UK
Program
(pdf-file)
Session 1 – Nuclear receptor biology in silico and in vitro
Design principles of nuclear receptor
signaling and nucleo-cytoplasmic shuttling
Alexey Kolodkin, Vrije Universiteit Amsterdam, The Netherlands
Validation of in vitro test systems for PXR
Ellen Wiedemann, University of Surrey, UK
PXR responsive elements
Marcin Buler, University of Oulu, Finland
Identification of functional PPAR
binding sites in target gene promoters
Tatjana Degenhardt, University of Kuopio, Finland
Identification of Vitamin D target
genes
Viola Woeckel, Erasmus University Medical Centre, Rotterdam, The
Netherlands
Session 2 – Co-regulators
Regulation of members of the
sirtuin gene family by PPARs
Aleksandra Tomaszewska, University of Kuopio, Finland
Mouse models for the study of
transcriptional co-regulation
Pedro Rocha, Max-Planck Institute for Molecular Genetics, Germany.
Session 3 – Metabolism and Energy
Effects of caloric restriction on
gene expression profiles in rat muscle and liver
Oita Radu Cristian, Unilever R&D, United Kingdom
Role of PPARa in fatty
acid-dependent gene regulation in heart
Anastasia Georgiadi, Wageningen University, The Netherlands
Effect of 1,25-dihydroxyvitamin D3
on Cystathionine-beta-synthase (CBS)
Carsten Kriebitzsch, Katholieke Universiteit Leuven, Belgium
Session 4 - Bone
Towards understanding the role of
PPARg in bone formation and osteoporosis: From controversies to novel
hypotheses
Claudia Bruedigam, Erasmus University Medical Centre, Rotterdam, The
Netherlands
In tune with the changes: searching
for phases in osteoblast differentiation
Katja Rybakova, Vrije Universiteit Amsterdam, The Netherlands
Session 5 – Cancer and Inflammation
NCoR1 activity in prostate
malignancies
Sebastiano Battaglia, University of Birmingham, UK
Search for novel vitamin D target
genes in human colon cancer cells
Fabio Pires, Instituto de Investigaciones Biomédicas, Spain
Effect of vitamin D treatment on
VDR target gene expression, in malignant and non malignant breast
epithelial cell lines
Carole Brosseau, St. George’s Hospital Medical School, UK
In vivo
and in vitro studies of 15d
_12,14 -Prostaglandin J2 regulation in mouse
Pedro Velica, University of Birmingham, UK
Evidence that nutritional calcium
affects the vitamin D system and markers for IBD
Thomas Nittke, Medical University of Vienna, Austria
Selection of VDR agonists for the
treatment of inflammatory bowel disease: in vitro and in vivo
experiments
Gilles Laverny, BioXell S.p.A., Italy
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