| |
NucSys
Consortium
Project Objectives
Overall Approach and Methodology
Research Tasks
Thematic Areas
Training and Transfer of Knowledge (ToK)
Vacancies
Meetings
NucSys
Newsletter
Lecture Material
ESR
Publications
|
|
Overall Approach
and Methodology
The
Consortium of twelve academic and two industrial partners is an
interdisciplinary co-operative of molecular, cellular and developmental
biologists, pharmacologists, physiologists, mathematicians and
bioinformaticians with a common goal to use systems biology, in order to
understand and then predict the actions of the NR superfamily in cells and
disease models. Combining the diverse expertise inherent in this structure
will enable the mathematical description of gene-nutrient interactions and
permit modelling of the impact of diet on health and the development of
disease. The Consortium aims to unite the
understanding of the activities of biological macromolecules and
metabolites to generate a unified paradigm capable of describing and
predicting complex processes in living cells and organisms. This requires
the integration and interpretation of large volumes of data from “omics”-based
studies (genomics, transcriptomics, proteomics, metabolomics and
physiomics) by the application of bioinformatics methods and systems
biology mathematical tools. |
|
