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Microarray analysis of nonhuman primates: validation of experimental models in neurobiological disorders

Markéta Marvanová(1), Jean Ménager(2), Erwan Bezard(3), Ronald E. Bontrop(4), Laurent Pradier(2), and Garry Wong(1)*

1 Functional Genomics and Bioinformatics Laboratory, Department of Neurobiology, A.I. Virtanen Institute, University of Kuopio, 70211 Kuopio, Finland,
2 Department of Neurodegenerative Diseases, Aventis Pharma, 94400 Vitry sur Seine, France,
3 Basal Gang, Department of Neurophysiology, CNRS UMR5543, 33076 Bordeaux, France, and
4 Biomedical Primate Research Centre, Lange Kleiweg 151, 2280 Rijswijk, The Netherlands.

* To whom correspondence should be addressed: garry.wong@uku.fi

Introduction
Group Leader
The Group
Research
Supplementary Info

University of
Kuopio


RAW DATA

Whole human brain

hbr 1a 
hbr 1b 
hbr 1c 

Human PFC

human 1a 
human 1b 
human 1c 

Chimpanzee PFC

chimpanzee 1a 
chimpanzee 1b 

Macaque PFC

macaque 1a 
macaque 1b 
macaque 2a 
macaque 2b 

Marmoset PFC

marmoset 1a 
marmoset 1b 
marmoset 2a 
marmoset 2b 

PRESENT GENES

HumanPFC (post mortem 6h) 
HumanPFC (post mortem 19h) 
ChimpanzeePFC-presentgenes 
OrangutanPFC-presentgenes 
MacaquePFC-presentgenes 
MarmosetPFC-presentgenes 

OVERLAPPING PRESENT GENES

human vs. NHPs 
human vs. apes genes 
guman vs. monkeys genes 
human vs. chipanzee genes 
human vs. orangutan genes 
human vs. macaque genes 
human vs. marmoset genes 

DIFFERENTIALLY EXPRESSED GENES (overlapping present genes in human and NHPs)

NHP vs. Human (>2 fold)

NHPs vs. human 
apes vs. human 
monkeys vs. human 
chimpanzee vs. human 
orangutan vs. human 
macaque vs. human 
marmoset vs. human 

NHP vs. Human (<2 fold)

NHPs vs. human 
apes vs. human 
monkeys vs. human 
chimpanzee vs. human 
orangutan vs. human 
macaque vs. human 
marmoset vs. human 

 

Page updated 12.12.2002 by M.S
Comments:  markus.storvik@uku.fi